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Upon diazepam-induced potentiation of GABA A R activity, diminished function of KCC2 leads to the accumulation of Cl inside the neuron and subsequent collapse of the Cl gradient (Fig

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The regulations will come into force in May next year if MPs agree. Deborah Arnott, chief executive of the anti-smoking charity Ash, said she was delighted the Government has resisted pressure from the tobacco industry

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Dr Dai said: Candy-flavoured e-cigarette products make up a substantial proportion of adolescent vapers, and sweet taste in e-cigarettes can suppress the harsh effects of nicotine and enhance its reinforcing effects, resulting in heightened brain cue-reactivity