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The nicotine in cigarettes causes blood vessels to constrict, raising blood pressure and increasing the risk of blood clots

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The BRE states: 'The reduction in exposure to second-hand smoke and the general improvement in public health, along with the reductions in losses to business in terms of sickness and other costs have made a favorable impact on the UK economy

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Tobacco use is associated with increased risk of developing various cancers, including lung, Laryngeal, esophagus, oral cavity, bladder, pancreatic, kidney, liver, stomach, Intestinal, cervical, Leukemia, and ovarian cancers Agudo et al., 2012McCormack et al., 2010Shiels et al., 2014