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Before this time most scientific bodies viewed smoking as a habit rather than an addiction.35 In the last 2 decades, knowledge of tobacco dependence has accumulated, and it is now widely recognised that nicotine is primarily responsible.36,37 Nicotine is an alkaloid found in tobacco, and when burnt is vaporised in tobacco smoke and delivered to the lungs

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Available from: Wei Xia, William Ho Cheung Li, Yuan Hui Luo, Ting Na Liang, Laurie Long Kwan Ho, Ankie Tan Cheung, Peige Song, The association between heated tobacco product use and cigarette cessation outcomes among youth smokers: A prospective cohort study, Journal of Substance Abuse Treatment, Volume 132, 2022, 108599, ISSN 0740-5472, Sun T, Anandan A, Lim CCW, East K, Xu SS, Quah ACK, et al