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Sam, I said, wouldnt you prefer that I paddle in the stern? I had put in many more hours than he had in canoes on rivers, so it seemed only correct to me that Sam should sit up in the bow and fend off branches and cottonmouths while I guided the canoe from the commanding position in the rear

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Conclusion Taken together, we demonstrated CS-induced mtNOX4/SOD2 mediated mtROS contributed to LF activation by decreasing PPAR/CPT1a-mediated FAO and lipophagy, which resulted from blocked autophagy flux