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Generation of NFE2L2 (i.e., NRF2) and KEAP1 knockdown stable cell lines GIPZ lentiviral human NFE2L2 shRNA glycerol stocks (Clone Id: V2LHS_239104, V2LHS_64253), lentiviral human KEAP1 shRNA glycerol stocks (Clone Id: V2LHS_254870, V3LHS_344984) and an empty vector (EV) control were obtained from Horizon Discovery

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Because DNA carries the recipe for making all protein components of the cell, damage to the cells DNA could change the entire function of the cell and may also cause problems in cell replication

Potential predictive value of TP53 and KRAS mutation status for response to PD-1 blockade immunotherapy in lung adenocarcinoma