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Key Takeaways Nicotine leaves the body quickly, but its metabolite lasts much longer: Nicotine itself is usually eliminated within 13 days, but cotinine (the primary metabolite tested for) can remain detectable for up to 10 days in blood and up to 3 weeks or longer in urine for heavy users

20 minutes - Heart rate and blood pressure drop 24 hours - Nicotine level in your body drops to zero A few days - The carbon monoxide level in your blood drops to normal 2-3 months - Blood circulation improves and lung function increases 1-12 months - Coughing and shortness of breath decrease after quitting 1-2 years - Your risk of heart attack reduces 3-6 years - The added risk of coronary heart disease drops by half 5-10 years - The risk of throat, mouth, and voice box cancer drops by half 10-15 years - Your risk of lung cancer drops by half to that of a person who still smokes Smoking makes cancer treatment difficult and ineffective

Second, expect the professionals to do more than just wipe down your walls

In fact, the distal segment of the large intestine can be affected mainly by the circulating components, where both CO and nicotine could modulate the inflammatory profile and leukocyte migration, and the immunomodulatory role would prevail over the impact on the mucosa (Figure 2)

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