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Learn more about the causes of IVF failure: Causes of IVF failure Premature menopause : The presence of chemicals such as nicotine, cyanide, and carbon monoxide in cigarette smoke increases the rate of egg loss

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Nicotine (a chemical in tobacco), tar (a partially combusted particulate matter produced by the burning of tobacco), and carbon monoxide (a colorless, odorless gas produced from the incomplete burning of tobacco) activate multiple biological pathways through which smoking increases risk for diseases of nearly all organs of the body