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Genome-wide DNA-binding profile of SRY-box transcription factor 3 (SOX3) in mouse testes

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doi: 10.3390/ijms25147573

replaced lysine residues at sites 117,161 and 162 of p53 with arginine residues in tumor cells to construct acetylation-deficient p53 3KR mutant mice, which did not regulate cell cycle and apoptosis like wtp53, but inhibited SLC7A11 expression and induced ferroptosis [76, 80]
