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They monopolize their products and then, as Berger puts it, market the hell out of them for unapproved and dangerous uses. Opioids are a drug class that includes opium derivatives like heroin (introduced by German drug maker Bayer in 1898), synthetics like fentanyl, and prescription painkillers like oxycodone (brand name: OxyContin)

For example, if a person smokes 2 packs of cigarettes per day for 10 years, it is equal to 20 pack-years

I hit the very last stretch and was so very happy for the downhill finish

Its adjusted revenue fell 2% to $5.41 billion, also missing Street forecasts