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Because of this difference in smoking prevalence, Americans from the bottom third in household income spend nearly twenty times more on cigarettes as a proportion of their income than those from the top third

These alterations contribute to systemic inflammation by increasing the production of pro-inflammatory cytokines, including interleukin (IL)-1, IL-6, IL-8, IL-13, tumor necrosis factor-alpha (TNF-), and transforming growth factor-beta 1 (TGF-1) [24]

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Similar proportions of subjects developed protective levels of anti-influenza antibodies between HUMIRA and placebo treatment groups