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We here demonstrate that nicotine affected growth plate chondrocytes through alpha7 nAChR to decrease matrix synthesis and to suppress hypertrophic differentiation, thereby delaying skeletal growth

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[DOI] [PubMed] [Google Scholar] Killen JD, Robinson TN, Ammerman S, Hayward C, Rogers J, Stone C, et al

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4, Next, he was forced to smoke two cigarettes with his nose