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Biol Psychiatry (2016) 79:9807

186 RoldoA.MelladoM

It is managed by HPC in partnership with the University of Pennsylvania
M.LichtensteinE

INTRODUCTION Tobacco smoking remains the second leading risk factor (top behavioural risk factor) contributing to the global burden of disease, which is estimated to include 7.1 million (95% CI: 6.837.37 million) deaths and 182 million (95% CI: 173193 million) DALYs in 2017 1
