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We included studies in this meta-analysis that: (1) assessed gray matter using structural MRI, (2) reported a set of coordinates (i.e., foci) from a between-subjects contrast comparing smokers to matched nonsmoking participants, (3) reported coordinates in a defined stereotaxic space (i.e., Talairach or Montreal Neurological Institute [MNI]), (4) performed a whole-brain analysis, and (5) provided sufficient information regarding characterization of smoking behaviors (e.g., pack-years, Fagerstrm Test of Nicotine Dependence [FTND] scores, years smoking, number of cigarettes smoked per day), basic demographics of the study samples (e.g., age, sex, N ), and data analysis strategies (e.g., smoothing parameters, statistical thresholds)

Youd have a horse or a mule that youd use to plow the field and get the rows arranged, then youd use a device like this for planting. The farmer and his familyeven kids, regardless of agewould don seed sacks and make their way through the rows in teams of two, the first on bended knee plunging his or her stick into the ground up to the rod and dropping in a few seeds, the second covering the holes over with dirt and adding water

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Those low yield brands were designed to show lower tar and nicotine yields on the federal trade Commission (FTC) smoking machine, but the machine did not mimic how humans actually used low yield cigarettes