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According to the irritating the throat and lungs increasing inflammation, or swelling, in the airways increasing airway resistance, creating less room for air to move in and out leading to hyperinflation, which occurs when air gets trapped inside the lungs, making it more difficult for the body to pull in fresh air damaging or scarring small blood vessels in the lungs According to the coughing wheezing overproduction of phlegm Some studies indicate that smoking cannabis may cause or worsen other lung conditions

Regression analyses were performed to determine the relative contribution of smoking and other demographic variables (e.g., age, years of education, baseline BMI and onset age) to explain the variance in negative symptom improvement

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