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Hypothalamic-pituitary-gonadal axis Nicotine can alter the hypothalamic-pituitary axis by stimulating the release of growth hormone, cortisol, vasopressin, and oxytocin, which in turn inhibit luteinizing hormone (LH) and prolactin [128]

The observed 48% reduction in genome size is thus likely to have occurred in the repetitive region of the genome

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