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Description
Participants were allocated to one of three groups for one month: those who continued smoking tobacco cigarettes, those who switched to e-cigarettes with nicotine and those who switched to e-cigarettes without nicotine
Examples include patches, gum, lozenges, inhalers, and mouth sprays

The first sign of trouble came in 1950 with the release of a study published by Doctors Ernst Wynder and Evarts Graham that linked cases of lung cancer to moderate to heavy cigarette smoking

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2011 doi: 10.1503/cmaj.110218
