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Cigarette smoking is the leading cause of preventable disease and death in the United States, accounting for more than 480,000 deaths every year

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In the same manner, thigmotaxis (time in the periphery of the open field) was increased over the 4 weeks of exposure to cigarette smoke in the NIC, NIC/ASA15, and NIC/ASA30 groups compared to the Control group (the period during which there was no ASA treatment)

Tobacco Nations high smoking rates, along with its relatively poor health outcomes and lack of access to care, make it a disadvantaged country within a country