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Additionally, pre-molecular and molecular genetic studies have demonstrated that several culprit genes are associated with an increased risk for developing schizophrenia with hundreds or even thousands of distinct genetic loci involved [90]

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The search terms included "UC," "smoking," "cigarettes," "mitigation," and "prevention." The reference lists, relevant reviews, and meta-analyses of all eligible articles were searched to prevent the omission of any relevant studies.The complete search strategy details can be found in Supplement 1