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In summary, CSC-induced cell death is highly concentration dependent: lower CSC concentrations of 50 g/ml induce apoptosis-like signalling whereas the apoptotic signalling in cells incubated with higher concentrations (100 g/ml) is stopped at the level of the mitochondria and redirected to programmed necrosis

Semple, "Improved Chewing Gum", published 28 December 1869 "William F

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