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The dose-dependent, unfavorable adverse effect profile (sedation and dry mouth) and limited efficacy of clonidine preclude its widespread use [57]

The risk of cancer of new current smokers in our study, albeit lower than those of the other smoking groups, was significantly increased relative to that of participants who had never smoked

doi: 10.1002/hed.23944

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That assumption is wrong: If youre a dual userwhich is some 70 percent of people using e-cigarettesyoure worse off than if you were just smoking because they pose an independent risk on top of any smoking that you do. Compared to people who solely smoked cigs (or e-cigs), dual users had higher levels of nicotine, heavy metals, and some carcinogens, in their urine, which raises their risk of cancer, addiction, and everything from lung disease to infertility beyond that of single-use smokers, according to a recent study conducted by the CDC