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The genotoxicity of 10 cigarette smoke condensate samples from a diverse set of cigarettes (including the K2R4F reference cigarette) and produced under different smoking-machine conditions was studied in four short-term assays: the Salmonella mutagenicity assay in frameshift strains TA98 and YG1041, the micronucleus and comet assays in L5178YTk 7.3.2C mouse lymphoma cells, and an assay for chromosomal aberrations in CHO-K1 cells (DeMarini et al
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