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Blocking cannabinoid CB1 receptors for the treatment of nicotine dependence: insights from pre-clinical and clinical studies
doi: 10.1016/j.amjmed.2008.01.016
When it was discovered, by accident, that the intense heat produced from the smoldering coals of a fire (rather than the fire itself) would turn the leaves of these plants a pleasing bright yellow, bright leaf tobacco was born and the regions tobacco fame began to take shape
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