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Smoking remains the leading cause of preventable death, according to the Centers for Disease Control and Prevention
We have a pretty good idea (vaping) causes lung damage, but they havent been doing it long enough to see what it will look like at age 50 or 60

The prevalence of tobacco exposure during pregnancy in this study was 3.7%, but cigarette smoking, second-hand smoke and smokeless tobacco were 0.4, 1.7 and 1.8%, respectively
Weakened immune system: Smoking exhausts immune defenses by exposing tissues to constant chemical irritation burden
Though generally safe, overdose or prolonged use can cause harm
