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Regarding long-term exploration through post hoc analysis of the ECLAT study, a 12-month prospective, randomized, controlled, double-blind trial in smokers with no intention to quit tobacco smoking who switched to e-cigarettes with and without nicotine, it was found that those who switched to e-cigarettes experienced a statistically significant reduction in long-term systolic blood pressure, with this reduction being more pronounced in smokers with elevated baseline blood pressure (35)

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[DOI] [PubMed] [Google Scholar] 39.Fay M.P., Proschan M.A

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