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Description
Implications on the dominant negative effect
Mechanistically, we found that overexpression of miR-34a-5p significantly reduced protein levels of HNF4 and CYP3A11, leading to a decrease in the severity of APAP-induced ALI
Mice with reduced levels of p53 protein exhibit the testicular giant-cell degenerative syndrome
(76) in the testes of mice fed a high-fat diet
Other studies have shown that p53 can also mediate HR by interacting with other proteins, such as the ATM/ATR checkpoint kinases [53]
