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[50] These derivatives can cause depurination, the removal of bases from the phosphodiester backbone of DNA, followed by inaccurate repair or replication of the apurinic site leading to mutation and eventually cancer
CrossRef Treatable traits in inflammatory bowel disease: a conceptual framework for personalized care Carolina B

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This reusability factor significantly alters the environmental equation, as the environmental cost of device manufacturing can be amortised over thousands of uses rather than single use

Ethical approval and informed consent Before collecting samples, Informed consent was obtained from all individuals and a survey was conducted to collect information on the type, duration and chronic diseases of smoking, as well as occupation
