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Posttranslational modification of histones involves covalent modification of specific sites and residues that form specific three-dimensional arrangements of nucleosomes that control the accessibility to transcriptional factors to genes to induce gene expression

Nature 415 , 4553 (2002)
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After 6 months, participants who switched had a statistically significant increase of 3.09 mg/dL in their HDL-C, which is approximately double the change that was seen at 3 months
14 : 423430 Wang M, McIntee E, Shi Y, Cheng G, Upadhyaya P, Villalta P, Hecht S
