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Retrieved 4 March 2020

It makes cigarettes more appealing, more addictive and more lethal

cancer cells, together with their surrounding stromal and inflammatory cells, form an inflammatory tumor microenvironment which contributes to proliferation, angiogenesis, metastasis and more (Greten and Grivennikov, 2019)

The peer-reviewed, two-part regression analysis is too complex to describe here in detail, and the technical discussion has been relegated to "Appendix A: The Econometric Analysis." In general terms, however, the model compares legal, per-capita sales of cigarettes to survey data on the percentage of smokers in each state (the survey data comes from the "Behavioral Risk Factor Surveillance System" administered by the Centers for Disease Control and Prevention)

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