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retail sales data, the number of unique e-cigarette products more than quadrupled from 453 to 2,023 between June 2021 and June 2022

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A 2023 updated Cochrane SR confirmed efficacy of bupropion for tobacco smoking cessation (and less so, nortriptyline), but it found no evidence in favour of SSRIs or venlafaxine

Alcohol abuse leads to addiction, mental health issues, and dangerous behaviors like drunk driving