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Gopal Grandhige, MD, FACS, Board-Certified Surgeon Last Reviewed: March 2, 2026 Acid reflux occurs when stomach acid flows backward into the esophagus, causing heartburn and discomfort

Yamanaka T, Imai T, Satoh R, Kawashima A, Takahashi M, Tomita K, Kubota K, Meshi T, Naito S, Ishikawa M (2002) Complete inhibition of tobamovirus multiplication by simultaneous mutations in two homologous host genes