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Would nicotine reduction have mental health consequences

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Then follow the dosage schedule unless your doctor tells you otherwise: days 1 to 6 take 1 Zyban tablet once a day day 7 increase your dose to 1 tablet twice a day week 2 continue taking 1 tablet twice a day and stop smoking this week on your chosen target day weeks 3 to 9 continue taking 1 tablet twice a day for up to 9 weeks If you have not quit smoking after 7 weeks of taking Zyban, your doctor will advise you to stop taking it

The EAGLES trial did not show a significant increase in neuropsychiatric adverse events attributable to varenicline or bupropion relative to nicotine patch or placebo (Anthenelli, 2016)