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The reduced cisplatin accumulation associated with cisplatin resistance is primarily due to reduced drug uptake rather than to increased drug efflux 44

We extracted 371 observations from 25 prospective cohort studies and 53 casecontrol studies across 25 locations (Supplementary Table 3) 5,6,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56,57,58,59,60,61,62,63,64,65,66,67,68,69,70,71,72,73,74,75,76,77,78,79,80,81,82,83,84,85,86,87,88,89,90,91,92,93,94,95,96,97,98,99,100,101,102,103,104,105,106,107