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The basic IQOS kit consists of three pieces: a pocket charger, the device itself, and the small tobacco sticks heated by the device (called HEETS in most countries, but HeatSticks in PMI's FDA applications)

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You should not smoke or use any other product containing nicotine while wearing the patch, since doing so will temporarily increase the level of nicotine in your blood

Cigarettes still kill nearly half a million people in the US each year 15 times the death toll from the opioid crisis

In addition to self-reported smoking status and CO measures taken at each visit, urinary anabasine and anatabine concentration will be used as the principle objective measure of the primary outcome (continuous abstinence from smoking during the last 4 weeks of treatment)