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The drug release kinetics can be explained by the Higuchi matrix model, which states that the drug release is controlled by the diffusion of a small liquid into a polymer matrix according to Fickian diffusion

Chemical analysis and in vitro toxicological evaluation of aerosol from a novel tobacco vapor product: a comparison with cigarette smoke

Nicotine is rapidly absorbed into the bloodstream after consumption, initiating a cascade of physiological responses

The drug schedules classified under Indiana law are based on medical use, abuse potential, and risk of dependency , mirroring the federal Controlled Substances Act under Indiana Code 35-48-2

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