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(Section 910(c)(4))4 This stringent standard essentially requires the applicant to demonstrate that, on balance, allowing the sale of the new product would likely reduce tobacco-related harms.25 Additionally, FDA is required to deny a PMTA for any product whose proposed labelling is false or misleading in any particular

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Drying Tobacco and Grading Leaves Freshly picked tobacco has a high moisture content making it impossible to ignite

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Chlorpyrifos: Used to manage a range of chewing and sucking insects, including caterpillars, beetles, and aphids