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Why nicotine has a much longer half-life in neonates than in adults, whereas the cotinine half-life is essentially the same in newborns and adults, might partially be explained by differing sensitivities of nicotine and cotinine clearances to changes in hepatic blood flow

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I just didn't like it." And while he has learned over the years to respect, at least in theory, that other actors have different methods, he remembers how as a teenager he'd see "somebody just grinding over in the corner trying to get in a frame of mindI just burst out laughing

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