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In the following years, chemists developed new strategies for the synthesis of nicotine, including strategies to produce pure S -nicotine, the form of nicotine prevalent in tobacco leaf (19, 23)

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Many people who switch to nicotine gum during quit attempts notice that urgent bathroom trips became less predictable and eventually less frequent

doi: 10.3389/fpls.2023.1273958 Received 07 August 2023 Accepted 02 October 2023 Published 23 November 2023 Volume 14 - 2023 Edited by Sezer Okay, Hacettepe University, Trkiye Reviewed by Ashwini Malla, Baiya Phytopharm Co., Ltd, Thailand