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[7] [8] The main reservation on the part of the network and producers was whether Alley would be funny enough to play the role, since she had a dramatic acting background rather than one in comedy

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Similar to the results our study literature about factors associated with dependence among e-cigarette users have found that nicotine dependence among e-cigarettes was associated with initiation of e-cigarette use at a younger age, e-cigarette use among friends and more recent use [20], as well frequency of use, concurrent cigarette smoking, use of nicotine e-liquids and higher nicotine concentrations [49]