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Acknowledgements This study was partially funded by NIH grants P30DA027827 (GB, LS, JM) and K23 AA016936 (JM)

4.2.3 Nicotine and CTLA-4 Mouse regulatory T cells (CD4+CD25+ cells) pre-treated with nicotine exhibited increased suppressive activity compared with regulatory T cells without nicotine treatment, reducing proliferation and IL-2 production by stimulated T cells in vitro

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