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There are 83 countries that have national/federal laws regulating e-cigarettes including laws related to the sale, age, advertisement, promotion, sponsorship, packaging with concern to health warning labeling and trademark, product regulation corresponding to nicotine concentration, safety, ingredients and flavors reporting taxation, use types and its toxicological evidences of e-cigarettes

Some e-cigarette manufacturers specifically target kids through cartridges that come in candy flavors and brightly-colored packaging

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Geoffroy-Perez A, Cordier S (2001) Fluid consumption and the risk of bladder cancer: results of a multicenter casecontrol study