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Tobacco This link opens in a new window Tobacco use is a major risk factor for cardiovascular and respiratory diseases, over 20 different types or subtypes of cancer, and many other debilitating health conditions

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In the 1980s PM routinely performed chemical analysis of smoke [36],[37], cytotoxicity testing (Ames and neutral red uptake tests) for mutagenicity [38],[39], and in vivo rodent toxicology studies [40][42], honing the techniques for performing these assays at their Institut fr Biologische Forschung (INBIFO) in Germany and Contract Research Center (CRC) in Belgium [13]

doi: 10.1161/CIRCRESAHA.107.164970, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 177.Mills N, Trnqvist H, Robinson SD, Gonzalez M, Darnley K, MacNee W, et al