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In the early 20th century, the average American smoked only 54 cigarettes per year

Long-term smoking is strongly linked to reduced life expectancy and serious health complications

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et al, Tobacco Control and the Reduction in Smoking-Related Premature Deaths in the United States, 1964-2012 , Journal of the American Medical Association , n o 311(2), 164-171 (lire en ligne)

Some participants switched from standard refillables (i.e