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The Q&A aims to make it clear what the current evidence indicates with respect to COVID-19 infection and severity, as well as where there are limitations in the availability of evidence

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However, there is a growing appreciation that, besides mitochondrial enzymatic activities and volume, the inner membrane architecture of the mitochondria, and the organization of the respiratory complexes demonstrate an important plasticity, and these cellular adaptations can occur independently from each other (48, 49)