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The physical symptoms of nicotine withdrawal (which include drowsiness, irritability, difficulty concentrating, anxiety, and craving for tobacco) are what prompt smokers to reach for a cigarette again and again

56 It has been suggested that any slight increase in effectiveness in smoking cessation by using e-cigarettes compared with other nicotine replacement products could be linked to satisfying of the habitual smoking actions, such as inhaling and bringing the hand to the mouth, 24 which are absent when using other nicotine replacement methods such as a nicotine patch

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Age, gender, underlying disease, depression, and anxiety were considered as possible confounders

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