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All products contain nicotine, which is dependence forming

Many airline pilots smoked, too

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The strength of the evidence ranges from conclusive which is the strongest to insufficient or no evidence. The report found conclusive evidence that the vast majority of e-cigarettes contain a wide variety of substances that are potentially toxic

Other studies have found nicotine capable of lowering inflammation in conditions like ulcerative colitis and rheumatoid arthritis, where excessive immune activation plays a central role in symptoms and disease progression
