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As a result, stools remain in the intestine longer, causing bacteria to release more gas
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In the follow-up period after almost four years, 23,745 new cases of hypertension were found, along with 13,179 new cases of type 2 diabetes

Extent of interaction and, by this, clinical relevance varies as some substrates are very sensitive to CYP 1A, e.g., duloxetine, others only moderately, e.g., clozapine, or weakly, e.g., valproate
