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Description
However, when alveolar cell lines are treated with cigarette smoke condensate an increase in the hypomethylation of transcriptional enhancer markers located adjacent to cg05575921 was found, 86 suggesting that cg05575921 and other sites in AHRR may be actively involved in the induction of gene regulatory elements
In particular, CYP1A2, which is important for the elimination of environmental chemicals, is strongly induced by PAHs
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