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This is one of the largest studies to date to assess the relationship of tobacco smoke exposure, as measured objectively by serum cotinine levels, with rhinitis in a community-based population of 1,315 children

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This addiction primarily stems from the presence of nicotine, a potent psychoactive substance found in tobacco, according to an article by the Center of Addiction and Mental Health titled Nicotine Dependence. The addictive nature of tobacco leads individuals to develop a tolerance, necessitating higher amounts to achieve the same effects, ultimately reinforcing the cycle of dependence

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