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Discussion This study identified multimodal brain patterns related to alcohol and tobacco use using AUDIT/FTND-guided fusion and investigated the associations between the identified brain patterns and symptoms and cognition in psychotic, depressive and developmental disorders

Social anxiety sufferers use alcohol to avoid physical symptoms, such as sweating and heart palpitations [19]

This mirrors national trends in clinical and non-clinical populations, underscoring the heightened vulnerability of rural and Appalachian residents for tobacco use and tobacco-related disease burden 25

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