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High prevalence of emphysema in middle-aged HIV-positive smokers, aidsmap.com, 8th January 2018

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According to these claims, and in contrast to other models of smoking progression, adolescents can lose autonomy over their smoking behavior after having smoked one puff in their lifetime and never having smoked again, and can become mentally and physically "hooked on nicotine" even if they have never smoked a puff

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